Skip to main content
Skip to main content

Comparison of Thermal and Non-Thermal Processing of Swine Feed and the Use of Selected Feed Additives on Inactivation of Porcine Epidemic Diarrhea Virus (PEDV)

Infection with porcine epidemic diarrhea virus (PEDV) causes diarrhea, vomiting, and high mortality in suckling pigs. Contaminated feed has been suggested as a vehicle of transmission for PEDV. The objective of this study was to compare thermal and electron beam processing, and the inclusion of feed additives on the inactivation of PEDV in feed. Feed samples were spiked with PEDV and then heated to 120-145°C for up to 30 min or irradiated at 0-50 kGy. Another set of feed samples spiked with PEDV and mixed with Ultracid P (Nutriad), Activate DA (Novus International), KEM-GEST (Kemin Agrifood), Acid Booster (Agri-Nutrition), sugar or salt was incubated at room temperature (~25°C) for up to 21 days. At the end of incubation, the virus titers were determined by inoculation of Vero-81 cells and the virus inactivation kinetics were modeled using the Weibull distribution model. The Weibull kinetic parameter delta represented the time or eBeam dose required to reduce virus concentration by 1 log. For thermal processing, delta values ranged from 16.52 min at 120°C to 1.30 min at 145°C. For eBeam processing, a target dose of 50 kGy reduced PEDV concentration by 3 log. All additives tested were effective in reducing the survival of PEDV when compared with the control sample (delta = 17.23 days). Activate DA (0.81) and KEM-GEST (3.28) produced the fastest inactivation. In conclusion, heating swine feed at temperatures over 130°C or eBeam processing of feed with a dose over 50 kGy are effective processing steps to reduce PEDV survival. Additionally, the inclusion of selected additives can decrease PEDV survivability. Trudeau MP, Verma H, Sampedro F, Urriola PE, Shurson GC, McKelvey J, Pillai SD, Goyal SM; Comparison of Thermal and Non-Thermal Processing of Swine Feed and the Use of Selected Feed Additives on Inactivation of Porcine Epidemic Diarrhea Virus (PEDV); PLoS One. 2016 Jun 24;11(6):e0158128. doi: 10.1371/journal.pone.0158128. eCollection 2016. PMID: 27341670 DOI: 10.1371/journal.pone.0158128 10.1371/journal.pone.0158128 Free full text

Are These Three Viruses Trending to Becoming More Common?

Recently, the number of calls and emails about growing pigs showing a wide range of neurologic signs of disease possibly related to three somewhat lesser-known viruses have increased. Veterinarians report growing pigs presenting symptoms that range from mild muscle tremors with mental alertness to lethargy and ataxia, with the most extreme cases progressing to paralysis and death. Reports of morbidity have been as low as 5 percent to as high as 20 percent. Case fatality rate has ranged from 30 percent to 100 percent. Among the possible infectious causes are porcine teschovirus (PTV), porcine sapelovirus (PSV) and atypical porcine pestivirus (APPV). Although these viruses are not new to the United States, historically confirmed cases have been reported infrequently. [Source: SHIC, June 29, 2016]

Are These Three Viruses Trending to Becoming More Common?

Recently, the number of calls and emails about growing pigs showing a wide range of neurologic signs of disease possibly related to three somewhat lesser-known viruses have increased. Veterinarians report growing pigs presenting symptoms that range from mild muscle tremors with mental alertness to lethargy and ataxia, with the most extreme cases progressing to paralysis and death. Reports of morbidity have been as low as 5 percent to as high as 20 percent. Case fatality rate has ranged from 30 percent to 100 percent. Among the possible infectious causes are porcine teschovirus (PTV), porcine sapelovirus (PSV) and atypical porcine pestivirus (APPV). Although these viruses are not new to the United States, historically confirmed cases have been reported infrequently. [Source: SHIC, June 29, 2016]

Steps Underway to Eliminate PED from Infected Manitoba Farms

Manitoba’s Chief Veterinary Officer says steps are being taken to clean and disinfect the three Manitoba swine farms that have been infected by Porcine Epidemic Diarrhea as quickly as possible. Since May 26th three Manitoba swine farms, including two sow barns and one finisher operation, have been confirmed infected by Porcine Epidemic Diarrhea. These are first cases reported in Western Canada in over 18 months. Dr. Megan Bergman, Manitoba’s Chief Veterinary Officer, says the main focus right now is to contain the outbreak and steps are being taken to clean up the infected farms. [Source: Farmscape.ca, June 22, 2016 by Bruce Cochran]

APHIS and CFIA Release Joint Response to Comments on Draft Framework for Foreign Animal Disease Zoning Arrangement

The U.S. Department of Agriculture’s (USDA) Animal and Plant Health Inspection Service (APHIS) and the Canadian Food Inspection Agency (CFIA) are making available a joint response to stakeholder comments received during an external consultation process to gather feedback on a draft framework for implementing and maintaining a foreign animal disease (FAD) zoning arrangement. [Source: USDA APHIS, June 23, 2016]

Obituary

Dr. Bruce H. Janke, DVM, PhD, age 68, of Ames, passed away on June 25, 2016 due to complications related to hereditary hemorrhagic telangiectasia (HHT) while at Mayo Methodist Hospital in Rochester, MN. A gathering of friends and family was held in Ames, IA Tuesday, June 28, followed by a memorial service on Wednesday, June 29.

Tee Up for the Foundation on August 25!

The AASV Foundation is returning to Veenker Memorial Golf Club in Ames, Iowa for its 2016 Golf Outing fundraiser, scheduled for Thursday, August 25. AASV members and industry supporters are invited to register a team (or individuals) to golf in support of the AASV Foundation! Previous events at Veenker have enjoyed record attendance. A number of companies have demonstrated their support of the Foundation by sponsoring a meal, beverages, or a golf hole, and the foundation is pleased to recognize Awards Dinner Sponsor Boehringer Ingelheim, Lunch Sponsor APC, Inc., Beverage Sponsor Pharmgate Animal Health, and Golf Hole Sponsors Insight Wealth Group, Merck Animal Health, National Pork Producers Council, Norbrook, Phibro Animal Health, and Zoetis.